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Horm Metab Res 1977; 9(4): 274-277
DOI: 10.1055/s-0028-1093551
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© Georg Thieme Verlag KG Stuttgart · New York

Effect of Bromocryptine on the Secretion of Thyrotropic Hormone (TSH), Prolactin (Pr), Human Growth Hormone (HGH), Thyroxine (T4) and Triiodothyroxine (T3) in Hypothyroidism

V.  Felt , J.  Nedvídková
  • Research Institute of Endocrinology, Prague, Czechoslovakia
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Publication Date:
23 December 2008 (online)

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Abstract

Bromocryptine (CB-154) virtually abolished the rise of serum Pr after TRH stimulation in hypothyroid and euthyroid subjects. The response of serum TSH to TRH stimulation was significantly depressed in hypothyroid but not in euthyroid subjects.

No significant changes of serum HGH, T4 and T3 after CB-154 were observed. The dual mode of action of CB-154 in pituitary and hypothalamus is discussed.

Key words

Hypothyroidism - TSH - Prolactin - HGH - T3 - T4 - TRH - Bromocryptine