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Horm Metab Res 1976; 8(6): 485-488
DOI: 10.1055/s-0028-1093602
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© Georg Thieme Verlag KG Stuttgart · New York

Parathyroid Hormone and Calcitonin: No Direct Effect on Vitamin D3-Mediated, Intestinal Calcium Absorptive Mechanism

R. A. Corradino
  • Department of Physical Biology, New York State College of Veterinary Medicine, Cornell University, Ithaca, New York, USA
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Publikationsdatum:
23. Dezember 2008 (online)

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Abstract

Embryonic chick duodenum maintained in organ culture responds to vitamin D3 in the culture medium by increased cyclic AMP concentration, de novo synthesis of a specific calcium-binding protein and by increased uptake and transmucosal transport of radiocalcium. The presence of bovine PTH, porcine or salmon calcitonin had no effect on these intestinal responses suggesting that these hormones may have no direct effect on the vitamin D3-mediated, intestinal calcium absorptive mechanism.

Key words

Organ Cultured Duodenum - Vitamin D3-Cyclic AMP - Calcium-Binding Protein - Calcium Transport - PTH - Calcitonin