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Horm Metab Res 1976; 8(5): 375-379
DOI: 10.1055/s-0028-1093617
DOI: 10.1055/s-0028-1093617
Originals
© Georg Thieme Verlag KG Stuttgart · New York
Effect of the Fatty Acid Composition of Ingested Fats on Rat Liver Intermediary Metabolism
Further Information
Publication History
Publication Date:
23 December 2008 (online)
Abstract
The influence of a single load of medium chain triglycerides (MCT) or long chain triglycerides (LCT) on different intermediary metabolites of the rat liver was studied.
Results showed that acetyl-CoA increased more after MCT than after LCT. MCT are more ketogenic than LCT. Mitochondrial and cytoplasmic redox state was greatly reduced after MCT. It is particularly interesting to note that MCT produced an increase in malate and citrate levels, whereas LCT had only a minor influence on these substances.
Key words
Medium and Long Chain Triglycerides - Rat Liver - Fat Ingestion - Ketone Bodies - Acetyl-CoA - Malate - Citrate - Redox State