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Horm Metab Res 1974; 6(6): 510-513
DOI: 10.1055/s-0028-1093799
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© Georg Thieme Verlag KG Stuttgart · New York

Linear Dose Dependent LH Release Following Intranasally Sprayed LRH

H. G. Dahlén , E.  Keller , H.P.G.  Schneider
  • Departments of Obstetrics and Gynecology, Universities of Ulm and Tübingen, Germany
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Publication History

Publication Date:
07 January 2009 (online)

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Abstract

A nasal spray delivering mg quantities of LRH per spray has been applied to male and female volunteers. Radioimmunoassayable plasma LH and FSH were recorded before and at different time intervals following intranasally sprayed LRH. In males a dose dependent LH release occurred over the range of 0.5-2.0 mg LRH. FSH release was not apparent. In females both LH and FSH release could be observed.

Key words

LRH - Nasal Spray - Males and Females