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Horm Metab Res 1974; 6(6): 488-491
DOI: 10.1055/s-0028-1093809
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© Georg Thieme Verlag KG Stuttgart · New York

The Effect of Muscular Exercise on Free Fatty Acids, Acetoacetate and 3-Hydroxybutyrate Blood Levels

A.  Boninsegna , G.  Federspil , C.  De Palo
  • Istituto di Chimica Biologica, Istituto di Semeiotica Medica dell'Università di Padova, Padova, Italy
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Publikationsdatum:
07. Januar 2009 (online)

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Abstract

It seemed of particular interest to study how the blood ketone bodies level could be influenced by the particular endocrine and metabolic situation which occurs during muscular exercise.

FFA increase during either the muscular work (60 min) or the following resting period (30 min). In the same experimental conditions, the blood ketone bodies (acetoacetate and 3-hydroxybutyrate) significantly decrease during muscular work, and increase again during the resting period.

In streptozotocin-treated rats muscular exercise decreases ketone bodies leveL

It is suggested that the decrease of acetoacetate and 3- hydroxybutyrate levels during the muscular work is due to an increased peripheral utilisation rather than to a decreased formation in the liver.

Key words

Muscular Exercise - Free Fatty Acids - Acetoacetate - 3-Hydroxybutyrate - Streptozotocin