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Horm Metab Res 1974; 6(6): 491-493
DOI: 10.1055/s-0028-1093810
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© Georg Thieme Verlag KG Stuttgart · New York

A Comparative Study on In Vivo Protein Synthesis by Liver of Pregnant and Non-pregnant Mice

U.  Tarachand , J.  Eapen
  • Biology and Agriculture Division, Bhabha Atomic Research Centre, Bombay, India
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Publication History

Publication Date:
07 January 2009 (online)

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Abstract

Incorporation of 14C-leucine, in vivo, into proteins of hepatic subcellular fractions as well as into proteins of free and membrane-bound ribosomes differs in pregnant and non-pregnant mice. Protein synthesis in nuclear, mitochondrial, microsomal and postmicrosomal supernatant fractions of liver is enhanced during pregnancy. There is a five-fold increase in labelling of proteins of both free and membrane-bound ribosomes of liver of pregnant mice in comparison with that of non-pregnant mice.

Key words

Pregnant Mice - Liver - Protein Synthesis - Cell Fractions - Ribosomes