Download PDF
Horm Metab Res 1974; 6(5): 410-414
DOI: 10.1055/s-0028-1093816
Originals

© Georg Thieme Verlag KG Stuttgart · New York

Inhibition of Releasing-Hormone-lnduced Secretion of TSH and LH by Calcitonin

E.  Leicht , G.  Birò , K. F. Weinges
  • Department of Internal Medicine, University of Saarland, Homburg/Saar, Germany
Further Information

Publication History

Publication Date:
07 January 2009 (online)

Also available at
  PDF Download  Permissions and Reprints

Abstract

Releasing hormone-induced secretion of TSH and LH was studied in 11 healthy subjects during infusion of physiological saline with and without salmon calcitonin (CT). Radioimmunologically measured serum concentrations of TSH and LH and time-concentration areas, assumed to be representative for hormone release, were found to be lower when CT was infused. As serum-calcium concentrations did not change significantly, a direct effect of CT on the secreting cells of the pituitary gland is postulated, probably mediated by an alteration in calcium fluxes.

Key words

Calcitonin - Thyroid-Stimulating Hormone (TSH) - Luteinizing Hormone (LH) - Thyrotropin-Releasing Hormone (TSH-RH) - Luteinizing Hormone-Releasing Hormone (LH-RH)