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Horm Metab Res 1974; 6(3): 234-237
DOI: 10.1055/s-0028-1093860
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© Georg Thieme Verlag KG Stuttgart · New York

Effect of Adrenaline on Plasma Vitamin C Levels in Normal Subjects

B. D. Cox , A. R. Clarkson [*] , M. J. Whichelow , P.  Rutland
  • Department of Medicine, Guy's Hospital, London, SEI 9RT, England
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Publication History

Publication Date:
08 January 2009 (online)

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Effect of Adrenaline on Plasma Vitamin C Levels in Normal SubjectsHorm Metab Res 1975; 7(01): 106-106
DOI: 10.1055/s-0028-1093758

Abstract

Studies of the effect of the intravenous injection of adrenaline on Vitamin C metabolism in healthy subjects showed that it produced a rapid and significant fall in plasma Vitamin C levels. The levels began to increase again before the end of the 30 minute adrenaline infusion.

The administration of a β-blocker - Propranolol - immediately prior to the adrenaline infusion completely abolished the Vitamin C response.

The changes in Vitamin C levels appeared unrelated to any adrenaline induced changes in the blood sugar and plasma insulin levels.

Key words

Adrenaline - β-Blockade - Glucose - Insulin - Ascorbic Acid

1 Present address: Renal Unit, Royal Adelaide Hospital, South Australia