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Horm Metab Res 1973; 5(1): 37-41
DOI: 10.1055/s-0028-1093999
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© Georg Thieme Verlag KG Stuttgart · New York

The Effect of Growth Hormone upon Glucose Metabolism and Cellularity in Rat Adipose Tissue[*]

B. R. Batchelor [**] , J. S. Stern
  • The Rockefeller University, New York, New York, USA
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Publication History

Publication Date:
07 January 2009 (online)

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Abstract

Intraperitoneal GH administration of 15 days duration to the post weanling rat leads to: (1) a depletion of epididymal fat stores, exclusively the result of a reduction in fat cell size since fat cell number is unaltered; (2) no change in glucose conversion to CO2 or triglyceride in the fat cell preparation when results are expressed on a per mg TG basis; but (3) depressed basal and insulin stimulated glucose conversion into CO2 and TG when results are expressed on a cellular basis.

Key words

Growth Hormone - Adipose Cellularity - Adipocyte Glucose Metabolism

1 This investigation was supported by United States Public Health Service Research Grant HD-02761 of the National Institute of Child Health and Human Development.

1 This investigation was supported by United States Public Health Service Research Grant HD-02761 of the National Institute of Child Health and Human Development.

2 This work was completed while B. Batchelor was the Glorney-Raisbeck Fellow in the Medical Sciences of the New York Academy of Medicine, 1971-1972.