Download PDF
Horm Metab Res 1971; 3(6): 437-442
DOI: 10.1055/s-0028-1094119
Originals

© Georg Thieme Verlag KG Stuttgart · New York

Effects of Altered Thyroid Function Upon Cortisol Secretion in Man

G.  Copinschi , R.  Leclercq , O. D. Bruno , A.  Cornil
  • Clinique Médicale, Laboratoires de Médecine Expérimentale, de Chimie Clinique et-de Physiopathologie, Université Libre de Bruxelles, Bruxelles, Belgium
Further Information

Publication History

Publication Date:
08 January 2009 (online)

Also available at
  PDF Download Buy Article Permissions and Reprints
Zoom Image

Abstract

The adrenocortical function was studied in adult patients with hyperthyroidism or with myxoedema. In 19 hyperthyroid women, the Cortisol secretion rate was significantly increased (30.6 ± 7.4 mg/d vs 17.8 ± 4.8 mg/d in normal controls); it was significantly decreased in 14 hypothyroid patients (13.7 ± 5.0 mg/d vs 20.5 ± 5.4 mg/d in matched controls). Changes in urinary excretion of Cortisol metabolites were more pronounced than in Cortisol secretion. Adrenocortical modifications were mostly reversible after recovery.

Key words

Cortisol Secretion in Hyperthyroidism - Cortisol Secretion in Hypothyroidism - Excretion of 17-Ketogenic Steroids in Hyperthyroidism - Excretion of 17-Ketogenic Steroids in Hypothyroidism