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Pharmacopsychiatry 1974; 7(2): 122-126
DOI: 10.1055/s-0028-1094410
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© Georg Thieme Verlag KG Stuttgart · New York

Genetic and Clinical Factors Associated with Course in Depression

Contributions to genetic aspectsG. Winokur
  • The University of Iowa Dept. of Psychiatry, 500 Newton Road, Iowa-City / Iowa / U.S.A.
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Publication Date:
20 January 2009 (online)

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Summary

Depression in female is associated with chronicity. The presence of an alcoholic father reliably predicts against long-term illnesses. Subsequent episodes of depression are more frequent in the male depressive particularly as aging occurs. These data are relevant to a theory of 2 types of depressive illness, depression spectrum disease and pure depressive disease.