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Horm Metab Res 1970; 2(6): 333-337
DOI: 10.1055/s-0028-1095049
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© Georg Thieme Verlag KG Stuttgart · New York

Studies on the Pituitary "Fettstoffwechselhormon" - III. The Corticotropic Activity of Some Lipolytic Effective Hog Pituitary Gland Fractions in Vivo

M.  Schleyer , W.  Evertz , K. H. Voigt , H. L. Fehm , J. D. Faulhaber , E. F. Pfeiffer
  • Department of Endocrinology and Metabolism, Department of Metabolism and Nutrition, Center of Medicine and Pediatrics, University of Ulm (Germany)
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Publikationsdatum:
08. Januar 2009 (online)

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Abstract

From the recently described lipolytically active pituitary gland fraction P IV we isolated three other fractions with different lipid mobilizing effects. These fractions were checked for their corticotropic activity as ACTH belongs to the most active lipolytic hormones. The applied bioassay for ACTH was based on the determination of the corticosterone increase in the adrenal vein blood of hypophysectomized rats. All of the isolated fractions showed corticotropic activity.

Key words

Lipolytic Hormone - Purification Procedure - Corticotropin - ACTH-Bioassay