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Horm Metab Res 1969; 1(6): 286-289
DOI: 10.1055/s-0028-1095130
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© Georg Thieme Verlag KG Stuttgart · New York

Studies on the Pituitary "Fettstoffwechselhormon" - II. The Lipolytic Activity of Various Pituitary Gland Fractions in Vitro

M.  Schleyer , K.  Straub , J.-D.  Faulhaber , E. F. Pfeiffer
  • Department of Endocrinology and Metabolism, Center of Medicine and Pediatrics, University of Ulm (Germany)
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Publication History

Publication Date:
08 January 2009 (online)

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Abstract

The lipolytic activity of crude hog pituitary extracts was studied on isolated fat cells of rats. The lipolytic activity as measured from the release of glycerol was compared to the standard pharmacologic agent 1-norepinephrine. All pituitary fractions stimulated lipolysis. The fraction with the highest lipolytic activity could be separated chromatographically as well as by gel-filtration to further lipolytic active components. An increase of lipolytic activity with reference to weight, could not be achieved employing those separation methods as earlier described by our group.

Key words

Lipolytic Hormone - Pituitary "Fettstoffwechselhormon" - Extraction Procedure