Electrical Stimulation of the Cochlea to Reduce Tinnitus

Richard S. Tyler; Jay Rubinstein; Tao Pan; Son-A. Chang; Stephanie A. Gogel; Anne Gehringer; Claudia Coelho

doi:10.1055/s-0028-1095892

Seminars in Hearing, Inhaltsverzeichnis

Semin Hear 2008; 29(4): 326-332
DOI: 10.1055/s-0028-1095892

Electrical Stimulation of the Cochlea to Reduce Tinnitus

Richard S. Tyler¹ , Jay Rubinstein² , Tao Pan¹ , Son-A Chang¹ , Stephanie A. Gogel¹ , Anne Gehringer¹ , Claudia Coelho¹

¹Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, Iowa
²Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, Washington

Abstract

ABSTRACT

This article reviews possible neural correlates of tinnitus, including an increase in rate, a decrease in rate, periodic activity, synchronous activity across neurons, and an edge between active and inactive neurons. We make some suggestions regarding how electrical current might alter these patterns of neural activity. For example, if tinnitus were represented with periodic neural activity, then electrical stimulation would need to disrupt this periodicity. Some cases of cochlear electrical stimulation are reviewed that show the tinnitus can be reduced or eliminated with cochlear electrical stimulation although it varies across individuals. Finally, after summarizing some key observations, we suggest some next steps to bring this into a clinical application.

KEYWORDS

Tinnitus - cochlear implants - electrical stimulation

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Referenzen

REFERENCES

1 Tyler R S, Babin R W. Tinnitus. In: Cummings CW, Fredrickson JM, Harker L, Krause CJ, Schuller DE Otolaryngology Head and Neck Surgery. St. Louis, MO; CV Mosby 1986: 3201-3217
2 Tyler R S. The psychoacoustical measurement of tinnitus. In: Tyler RS Tinnitus Handbook. San Diego, CA; Singular 2000: 149-179
3 Stouffer J L, Tyler R S. Characterization of tinnitus by tinnitus patients. J Speech Hear Disord. 1990; 55 439-453
4 Tyler R S. Neurophysiological Models, Psychological Models, and Treatments for Tinnitus. In: Tyler RS Tinnitus Treatment: Clinical Protocols. New York, NY; Thieme 2006: 1-22
5 Cacace A T, Lovely T J, Winter D F, Parnes S M, McFarland D J. Auditory perceptual and visual-spatial characteristics of gaze-evoked tinnitus. Audiology. 1994; 33 291-303
6 Kaltenbach J A. Neurophysiologic mechanisms of tinnitus. J Am Acad Audiol. 2000; 11(3) 125-137
7 Shore S E. Sensory nuclei in tinnitus. In: Snow J Tinnitus: Theory and Management. Hamilton, Ontario, Canada; BC Decker 2004
8 Tyler R S. Invited discussant. Tinnitus. In: Evered D, Lawrenson G Tinnitus (Ciba Foundation Symposium 85). London, UK; Pitman 1981: 136-137
9 Tyler R S, Conrad-Armes D. Masking of tinnitus compared to the masking of pure tones. J Speech Hear Res. 1984; 27 106-111
10 Kiang N YS, Moxon E C, Levine R A. Auditory-nerve activity in cats with normal and abnormal cochleas. In: Wolstenholme GEW, Knight J Sensorineural Hearing Loss. London, UK; Churchill Livingston 1970: 241-268
11 Eggermont J J. Tinnitus: some thought about its origin. J Laryngol Otol. 1984; (suppl 9) 31
12 Eggermont J J. Psychological mechanisms and neural models. In: Tyler RS Tinnitus Handbook. San Diego, CA; Singular 2000: 85-122
13 Moller A R. Pathophysiology of tinnitus. Ann Otol Rhinol Laryngol. 1984; 93 39-44
14 Salvi R J, Wang J, Powers N J. Plasticity and reorganization in the auditory brainstem: implications for tinnitus. In: Reich GE, Vernon JE Proceedings of the Fifth International Tinnitus Seminar. Portland, OR; American Tinnitus Association 1996: 457-466
15 Abbas P J. Electrophysiology. In: RS Tyler Cochlear Implants: Audiological Foundations. San Diego, CA; Singular 1993: 317-355
16 Rubinstein J T, Tyler R S, Johnson A, Brown C J. Electrical suppression of tinnitus with high-rate pulse trains. Otol Neurotol. 2003; 24 478-485
17 Ito J, Sakakihara J. Suppression of tinnitus by cochlear implantation. Am J Otolaryngol. 1994; 15 145-148
18 Demajumdar R, Stoddart R, Donaldson I, Proops D W. Tinnitus, cochlear implants and how they affect patients. J Laryngol Otol Suppl. 1999; 24 24-26
19 Tyler R S, Kelsay D. Advantages and disadvantages reported by some of the better cochlear-implant patients. Am J Otol. 1990; 11 282-289
20 Tyler R S. Tinnitus in the profoundly hearing-impaired and the effects of cochlear implants. Ann Otol Rhinol Laryngol Suppl. 1995; 165 25-30
21 Gibson W PR. The effect of electrical stimulation and cochlear implantation on tinnitus. In: Aran JM, Dauman R Proceedings of the Fourth International Tinnitus Seminar, Bordeaux, 1991. Amsterdam, The Netherlands/New York, NY; Kugler 1992: 403-408
22 Kim H N, Shim Y J, Kim Y M, Kim E S. Effect of electrical stimulation on tinnitus in the profoundly deaf. In: Reich GE, Vernon J Proceedings of the Fifth International Tinnitus Seminar. Portland, OR; American Tinnitus Association 1995: 508-517
23 Dauman R. Electrical stimulation for tinnitus suppression. In: Tyler RS Tinnitus Handbook. San Diego, CA; Singular 2000: 377-398
24 Quaranta N, Wagstaff S, Baguley D M. Tinnitus and cochlear implantation. Int J Audiol. 2004; 43 245-251
25 Rubinstein J T, Tyler R S. Electrical suppression of tinnitus. In: Snow J Tinnitus: Theory and Management. Hamilton, Ontario, Canada; BC Decker 2004: 326-335
26 Portmann D, Felix F, Negrevergne M et al.. Bilateral cochlear implantation in a patient with long-term deafness. Rev Laryngol Otol Rhinol (Bord). 2007; 128(1–2) 65-68
27 Dobie R A, Hoberg K E, Rees T. Electrical tinnitus suppression: a double-blind crossover study. Otolaryngol Head Neck Surg. 1986; 95 319-323
28 Matsushima J, Sakai N, Takeichi N et al.. Implanted electrical tinnitus suppressor. In: Reich GE, Vernon JA Proceedings of the Fifth International Tinnitus Seminar. Portland, OR; American Tinnitus Association 1996: 329-334
29 Okusa M, Shiraishi T, Kubo T, Matsunaga T. Tinnitus suppression by electrical promontory stimulation in sensorineural deaf patients. Acta Otolaryngol Suppl. 1993; 501 54-58
30 Ruckenstein M J, Hedgepeth C, Rafter K O, Montes M L, Bigelow D C. Tinnitus suppression in patients with cochlear implants. Otol Neurotol. 2001; 22(2) 200-204
31 Miyamoto R T, Bichey B G. Cochlear implantation for tinnitus suppression. Otolaryngol Clin North Am. 2003; 36(2) 345-352
32 Kou B S, Ship D B, Nedzelski J M. Subjective benefits reported by adult Nucleus 22-channel cochlear implant users. J Otolaryngol. 1994; 23(1) 8-14
33 Souliere Jr C R, Kileny P R, Zwolan T A, Kemink J L. Tinnitus suppression following cochlear implantation. A multifactorial investigation. Arch Otolaryngol Head Neck Surg. 1992; 118(12) 1291-1297
34 Zwolan T A, Kileny P R, Souliere C R, Kemink J L. Tinnitus suppression following cochlear implantation. In: Aran J-M, Dauman R Tinnitus 91: Proceedings of the Fourth International Tinnitus Seminar. Amsterdam, The Netherlands; Kugler 1992: 423-426
35 Kuk F K, Tyler R S, Rustad N, Harker L A, Tye-Murray N. Alternating current at the eardrum for tinnitus reduction. J Speech Hear Res. 1989; 32 393-400
36 Hazell J WP, Meerton L J, Conway M J. Electrical tinnitus suppression (ETS) with a single channel cochlear implant. J Laryngol Otol Suppl. 1989; 18 39-44
37 McKerrow W S, Schreiner C E, Snyder R L, Merzenich M M, Toner J G. Tinnitus suppression by cochlear implants. Ann Otol Rhinol Laryngol. 1991; 100 552-558
38 Dauman R, Tyler R S, Aran J M. Intracochlear electrical tinnitus reduction. Acta Otolaryngol. 1993; 113 291-295
39 Dauman R, Tyler R S. Tinnitus suppression in cochlear implant users. Adv Otorhinolaryngol. 1993; 48 168-173

Richard S TylerPh.D.

Department of Otolaryngology-Head and Neck Surgery, University of Iowa

200 Hawkins Drive (21201 PFP), Iowa City, IA 52242-1078

eMail: rich-tyler@uiowa.edu