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Thorac Cardiovasc Surg 1979; 27(3): 187-189
DOI: 10.1055/s-0028-1096241
Copyright © 1979 by Georg Thieme Verlag Stuttgart

Heart Valve Replacement with the St. Jude Medical Prosthesis — First Clinical Results —

F. W. Hehrlein, M. G. Gottwik, M. Schlepper, G. Fraedrich
  • Department of Cardiovascular Surgery, Justus-Liebig-University, Giessen, and Kerckhoff-Clinic, Bad Nauheim
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Publication History

Publication Date:
11 December 2008 (online)

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Summary

Starting in February 1978 52 St. Jude Medical Prostheses have been implanted in 47 patients (age 13–73 years) in aortic, mitral and tricuspid positions. Perioperative death occurred in 3 cases. Post mortem examination of these patients showed unimpaired valvular function. There were no other complications in an accumulated total valve time of approximately 300 months. Prior to surgery and post-operatively, several hemolytic parameters were analyzed. There was only a mild elevation in Serum LDH (285 ± 10 iV/L). Fifteen patients underwent recatheterization 3 months postoperatively. The mitral valves did not reveal an enddiastolic gradient at rest, while the aortic valves had a peak to peak gradient of 8 ± 2.1 mmHg. A standardized stress consisting of an infusion of isoproterenol was used. The results were compared to results obtained in patients with Björk-Shiley prostheses under identical conditions and did not show a significant difference. The preliminary hemodynamic findings correlate with preceding in vitro results and preclinical data, and the first clinical experience is promising.

Key-Words:

Heart valve replacement - Bileaflet heart valve prosthesis - Recatheterization