Abstract
Urinary cyclic AMP was studied in 22 female and in 6 male hyperthyroid normocalcemic patients and in 3 hyperthyroid hypercalcemic men. Cyclic AMP/creatinine ratios were elevated both in female (4.12±0.26 µmoles/gm creatinine) and male (3.92±0.41 µmoles/gm creatinine) hyperthyroid normocalcemic patients as compared with normal female and male controls (2.85±0.20 and 2.54±0.14 µmoles/gm crcatinine, respectively). However, there was no difference in the 24-hour urinary cyclic AMP excretion of both hyperthyroid and normal subjects. The hyperthyroid hypercalcemic men excreted less (2.47±0.19 µmoles/24 hr) cyclic AMP/24 hr than the normal male controls. In the thirteen female patients, studied when euthyroid, the cyclic AMP/creatinine ratio was normalised.
Key words
Urinary Cyclic AMP - Urinary Creatinine - Normocalcemic and Hypercalcemic Hyperthyroidism
