Studies on Quercus infectoria; Isolation of Syringic Acid and Determination of its Central Depressive Activity

Mohammad S. Dar; M. Ikram

doi:10.1055/s-0028-1097197

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Planta Med 1979; 35(2): 156-161
DOI: 10.1055/s-0028-1097197

Research Articles

Studies on Quercus infectoria; Isolation of Syringic Acid and Determination of its Central Depressive Activity

Mohammad S. Dar, M. Ikram¹

Department of Pharmacology, School of Medicine, Pahlavi University, Shiraz, Iran.

1 Present Address: Dr. M. Ikram, Principal Scientific Officer, Pakistan Council of Scientific and Industrial Research Laboratories, Post Office Peshawar University, Peshawar, Pakistan.

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Publication History

Publication Date:
13 January 2009 (online)

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Abstract

The methanolic fraction of the galls of Quercus infectoria exhibited interesting neuropharmacological activity in laboratory animals. Chemical characterization of the CNS active component was undertaken. Based on IR and m.p. criteria, the isolated substance has been identified as syringic acid.

The neuropharmacology of isolated and pure syringic acid was studied and the data presented suggest significant local anaesthetic and sedative activity of the compound.

Key Word Index

Quercus infectoria - Galls - Syringic Acid - Neuropharmacological Acitivity