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Planta Med 1979; 37(10): 131-136
DOI: 10.1055/s-0028-1097312
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Pyrrolizidinalkaloide aus Senecio vernalis

Pyrrolizidine–Alkaloids from Senecio vernalisE. Röder, H. Wiedenfeld, U. Pastewka*
  • Pharmazeutisches Institut der Universität Bonn, Bundesrepublik Deutschland
* Teilergebnisse der beabsichtigten Dissertation U. PASTEWKA, Universität Bonn.
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Publication History

Publication Date:
13 January 2009 (online)

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Abstract

From Senecio vernalis four pyrrolizidine alcaloids were isolated. Three turned out to be the previoulsy described senecinine, senkirkine and retrorsine. Spectroscopic investigations showed the structure of the fourth compound to be 5–hydroxy–3,4–dimethyl–hex–1–en–2,5–dicarbonyl–retronecine (senecivernine). Using gaschromatography the quantitative ratio of the 4 alcaloids in S. vernalis was measured.

Key Word Index

Senecio vernalis - Asteraceae - Pyrrolizidine Alkaloids - Senecivernine