Inhibition of Platelet Aggregation by „Guggulu” Steroids

L. Mester; M. Mester; Swarn Nityanand

doi:10.1055/s-0028-1097351

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Planta Med 1979; 37(12): 367-369
DOI: 10.1055/s-0028-1097351

Research Articles

Inhibition of Platelet Aggregation by „Guggulu” Steroids

L. Mester¹ , M. Mester¹ , Swarn Nityanand²

¹Institut de Chimie des Substances Naturelles, Gif–sur–Yvette, France.
²Central Drug Research Institute, Lucknow, India.

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Publication History

Publication Date:
13 January 2009 (online)

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Abstract

Purified steroidal fractions of „guggulu” show a marked inhibition of ADP, adrenaline and serotonin induced platelet aggregation. Their inhibitory effect is comparable to the effect of „Clofibrate”.

Key Word Index

Commiphora mukul - Burseraceae - Platelet Aggregation - ADP - Adrenaline - Serotonin - Clofibrate - Steroids