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Planta Med 1978; 33(2): 188-192
DOI: 10.1055/s-0028-1097376

© Georg Thieme Verlag Stuttgart · New York

Indirect Identification of 4,21–Dehydrocorynantheine Aldehyde as an Intermediate in the Biosynthesis of Ajmalicine and Related Alkaloids

J. Stöckigt1 , M. Rueffer1 , M. H. Zenk1 , G.–A. Hoyer2
  • 1Lehrstuhl für Pflanzenphysiologie, Ruhr–Universität Bochum.
  • 2Schering AG., Department für Spectrometrie und Quantenchemie, Berlin Federal Republic of Germany
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Publication History

Publication Date:
13 January 2009 (online)

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Abstract

In the pesence of BH4 – an enzyme preparation of Catharanthus roseus cell suspension cultures transformes strictosidine (1), to sitsirikine (11a) and 16–isositsirikine (11b) which are derived from 4,21–dehydrocorynantheine aldehyde (5), an intermediate in the formation of heteroyohimbine type alkaloids.

Key Word Index

Catharanthus roseus - Cell Suspension Cultures - Enzymatic Formations - Sitsirikine - 4,21–Dehydrocoryantheine Aldehyde - Heteroyohimbine Type Alkaloids