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Planta Med 1978; 34(5): 26-36
DOI: 10.1055/s-0028-1097410
Research Articles

© Georg Thieme Verlag Stuttgart · New York

The Mitragyna Species of Asia

Part XXXI – The Alkaloids of Mitragyna speciosa Korth from ThailandE. J. Shellard, P. J. Houghton, Masechaba Resha
  • Pharmacognosy Research Laboratories, Chelsea College, University of London.
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Publication History

Publication Date:
13 January 2009 (online)

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Abstract

In addition to the previously reported alkaloids from Mitragyna speciosa a number of additional oxindole alkaloids were isolated, three of which are new. These have been named mitrafoline, isomitrafoline and isospeciofoline. Mitragynine oxindoles A and B were found for the first time in plant material while corynoxeine and the corynoxines were found for the first time in the genus Mitragyna. Examination of thirteen monthly samples of leaves showed that mitragynine and paynantheine remained the dominant indole alkaloids of the mature plant throughout the entire period of collection.

Key Word Index

Mitragyna speciosa - Rubiaceae - Oxindole Alkaloids - Mitrafoline - Isomitrafoline - Isospeciofoline