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Planta Med 1978; 34(6): 192-202
DOI: 10.1055/s-0028-1097435
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Extraktion von Alkaloiden mit überkritischen Gasen in direkter Kopplung mit der Dünnschicht–Chromatographie

Extraction of Alkaloids with Supercritical Gases in Direct Coupling with Thin–Layer ChromatographyEgon Stahl, Eberhard Willing
  • Pharmakognosie und Analytische Phytochemie der Universität des Saarlandes, D–6600 Saarbrücken, Bundesrepublik Deutschland.
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Publication Date:
13 January 2009 (online)

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Abstract

The extraction power of supercritical carbon dioxide and nitrous oxide for pure alkaloids, their salts, and their corresponding medicinal plants was examined. The main alkaloids of the following plants were selected : Areca, China, Colchicum, Qonium, Ephedra, Ipecacuanha, Nicotiana, Opium, Rauwolfia, Atropa and Catharanthus. The test were done with a micro extraction apparatus coupled directly with TLC, mainly m the pressure region between 80 and 200 bar, at a temperature of 40° Celsius.

The results show a relation between extractability and constitution of the alkaloids. Supercritical carbon dioxide has a good extraction power for certain alkaloids; in comparison to this, fluid nitrous oxide, however, proves to be superior.

Key Word Index

Fluid Extraction - Supercritical Gases - TLC–Coupling