ACTIVITÉ ANTIBIOTIQUE ET CYTOTOXIQUE DE LA CNICINE ET DE SES PRODUITS D'HYDROLYSE

R. Vanhaelen–Fastré; M. Vanhaelen

doi:10.1055/s-0028-1097650

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Planta Med 1976; 29(2): 179-189
DOI: 10.1055/s-0028-1097650

ACTIVITÉ ANTIBIOTIQUE ET CYTOTOXIQUE DE LA CNICINE ET DE SES PRODUITS D'HYDROLYSE

Relation Structure Chimique – Activité BiologiqueAntibiotic and cytotoxic activity of cnicin and of its hydrolysis productsChemical structure – biological activity relationshipR. Vanhaelen–Fastré, M. Vanhaelen

Université Libre de Bruxelles, Institut de Pharmacie, Bruxelles, Belgique

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Publication Date:
13 January 2009 (online)

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Abstract

Cnicin chemical structure – biological activity (antibiotic and cytotoxic) relationship study is undertaken by comparative tests performed with the hydrolysis products of this sesquiterpene lactone.

Cnicin does not seem to be able to form an intercalating complex with DNA.