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Planta Med 1976; 30(8): 297-302
DOI: 10.1055/s-0028-1097733
© Georg Thieme Verlag Stuttgart · New York

HYPOTENSIVE PRINCIPLE OF ASTRAGALUS AND HEDYSARUM ROOTS1

Hiroshi Hikino, Shinji Funayama, Katsuya Endo
  • Pharmaceutical Institute, Tohoku University, Sendai, Japan
1 Part 2 in the series on the validity of the Oriental medicines.
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Publication Date:
13 January 2009 (online)

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Abstract

Fractionation of the extract of an Oriental medicine „ogi”, Astragalus membranaceus roots, was performed monitored by the hypotensive activity against the urethane anesthetized rat to afford γ–aminobutyric acid as the active principle. The hypotensive activity of various preparations of the crude drug „ogi”, the roots of Astragalus spp. and Hedysarum spp., showed a good correlation with the content of ?-aminobutyric acid.