Zusammenfassung
Striae distensae stellen ein überaus häufiges kosmetisches Problem dar. Seit der Einführung
der evidenzbasierten Medizin wurden zunehmend wissenschaftlich fundierte Erkenntnisse
bezüglich der Prophylaxe und Therapie von Striae distensae erarbeitet. Humorale, mechanische
und genetische Faktoren spielen eine entscheidende Rolle in ihrer Entstehung. In Abhängigkeit
des Entwicklungsstands von Striae distensae werden unterschiedliche Behandlungsansätze
als wirksam dokumentiert. Hierzu zählen verschiedene Mittel zur örtlichen Anwendung
vom Typ der Dermatika wie Kosmetika und physikalische Methoden wie Laser und in jüngster
Zeit auch Radiofrequenz (Thermage). Für die Prophylaxe zeigte sich ein äußeres Mittel
mit einem Extrakt aus Centella asiatica als geeignet. Weitere wissenschaftlich fundierte Studien sind nötig zur endgültigen
Klärung der Pathophysiologie und zur Entwicklung sicherer und standardisierter Behandlungskonzepte.
Abstract
Striae distensae are a very common cosmetic problem. Since the introduction of evidence-based
medicine, knowledge about the prevention and treatment of striae distensae has increased.
Humoral, mechanical and genetic factors all play a crucial role in their formation.
Different treatment approaches have been reported to be effective, depending on the
extent of the striae distensae. Possible treatments include various cosmetic-type
local applications of dermatological creams as well as physical methods such as laser
therapy and, more recently, radio frequency ablation (thermage). For the prophylaxis,
externally applied products containing extracts from Centella asiatica have been found
to be suitable. More scientific studies are needed for the final clarification of
the pathophysiology and for the development of safe and standardized treatment approaches.
Schlüsselwörter
Striae distensae - Schwangerschaftsstreifen - Prophylaxe - Centella asiatica
Key words
striae distensae - stretch marks - prophylaxis - Centella asiatica
Literatur
- 1
Salter S A, Kimball A B.
Striae gravidarum.
Clinics Dermatol.
2006;
24
97-100
- 2
Klehr N.
Striae cutis atrophicae: morphokinetic examinations in vitro.
Acta Derm Venereol.
1985;
65
105-108
- 3
Garcia H L.
Dermatological complications of obesity.
Am J Clin Dermatol.
2002;
3
497-506
- 4
Viennet C, Bride J, Armbruster V. et al .
Contractile forces generated by striae distensae fibroblasts embedded in collagen
lattices.
Arch Dermatol Res.
2005;
297
10-17
- 5 Burrows N P, Lovell C R.
Disorders of connective tissue. Burns T, Breathnach S, Cox N, Griffith C, eds. Rook's textbook of dermatology, 7th
ed. Oxford; Blackwell Science 2004: 46-47
- 6
Cho S, Park E S, Lee D H. et al .
Clinical features and risk factors for striae distensae in Korean adolescents.
JEADV.
2006;
20
1108-1113
- 7
Elson M L.
Treatment of striae distensae with topical tretinoin.
J Dermatol Surg Oncol.
1990;
16
267-270
- 8
Zheng P, Lavker R M, Kligman A M.
Anatomy of striae.
Brit J Dermatol.
1985;
112
185-193
- 9
Mahabir R C, Peterson B D.
Two cases of striae distensae after submuscular augmentation mammaplasty.
Plastic Reconstr Surg.
2001;
108
753-756
- 10
Nigam P K.
Striae cutis distensae.
Int J Dermatol.
1989;
28
426-428
- 11
Shuster S.
The cause of striae distensae.
Acta Derm Venereol.
1979;
59
161-169
- 12
Atwal G SS, Manku L K, Griffiths C EM. et al .
Striae gravidarum in primiparae.
Brit J Dermatol.
2006;
155
965-969
- 13
Watson R EB, Parry E J, Humphries J D. et al .
Fibrillin microfibrils are reduced in skin exhibiting striae distensae.
Brit J Dermatol.
1998;
138
931-937
- 14
Chang A LS, Agredano Y Z, Kimball A B.
Risk factors associated with striae gravidarum.
J Am Acad Dermatol.
2004;
51
881-885
- 15
Hernández-Pérez E, Colombo-Charrier E, Valencia-Ibiett E.
Intense pulsed light in the treatment of striae distensae.
Dermatol Surg.
2002;
28
1124-1130
- 16
Sheu H M, YU H S, Chang C H.
Mast cell degranulation and elastolysis in the early stage of striae distensae.
J Cutan Pathol.
1991;
18
410-416
- 17
Chernosky M E, Knox J M.
Atrophic striae after occlusive corticosteroid therapy.
Arch Dermatol.
1964;
90
15-19
- 18
Arem A J, Kischer C W.
Analysis of striae.
Plast Reconstr Surg.
1980;
65
1
- 19
Kang S, Kim K J, Griffiths C E. et al .
Topical tretinoin (retinoic acid) improves early stretch marks.
Arch Dermatol.
1996;
132
519-526
- 20
McGormack M C, Nowak K C, Koch R J.
The effect of copper tripeptide and tretinoin on growth factor production in a serum-free
fibroblast model.
Arch Facial Plast Surg.
2001;
3
28-32
- 21
Ash K, Lord J, Zukowski M. et al .
Comparison of topical therapy for striae alba (20 % glycolic acid/0.05 % tretinoin
versus 20 % glycolic acid/10 % L-ascorbic acid).
Dermatol Surg.
1998;
24
849-856
- 22
McDaniel D H, Ash K, Zukowski M.
Treatment of stretch marks with the 585-nm flashlamp-pumped pulsed dye laser.
Dermatol Surg.
1996;
22
332-337
- 23
Castor D J, Abergel R P, Keeker C. et al .
Effects of the Nd : YAG Laser on DNA synthesis and collagen production in human skin
fibroblast cultures.
Ann Plast Surg Oncol.
1983;
11
214-221
- 24
Abergel R P, Lyons R F, Castel J C. et al .
Biostimulation of wound healing by lasers: experimental approaches in animal models
and in fibroblast cultures.
J Dermatol Surg Oncol.
1987;
11
214-221
- 25
Alster T S, Williams C M.
Treatment of keloid sternotomy scars with 585 nm flashlamp-pumped pulsed dye laser.
Lancet.
1995;
345
1198-1200
- 26
Jiménez G P, Flores F, Berman B. et al .
Treatment of striae rubra and striae alba with the 585 nm pulsed-dye laser.
Dermatol Surg.
2003;
29
362-365
- 27
Nouri K, Romagosa R, Chartier T. et al .
Comparison of the 585 nm pulse dye laser and the short pulsed CO2 laser in the treatment
of striae distensae in skin types IV and VI.
Dermatol Surg.
1999;
25
368-370
- 28
Suh D H, Chang K Y, Son H C. et al .
Radiofrequency and 585 nm pulsed dye laser treatment of striae distensae: a report
of 37 Asian patients.
Dermatol Surg.
2007;
33
29-34
- 29
Goldberg D J, Marmur E S, Schumlts C. et al .
Histologic and ultrastructural analysis of ultraviolet B laser and light source treatment
of leukoderma in striae distensae.
Dermatol Surg.
2005;
31
385-387
- 30
Alexiades-Armenakas M R, Bernstein L J, Friedman P M. et al .
The safety and efficacy of the 308 nm excimer laser for pigment correction of hypopigmented
scars and striae albae.
Arch Dermatol.
2004;
140
955-960
- 31
Mallol J, Bleda M A, Costa D. et al .
Prophylaxis of striae gravidarum with a topical formulation. A double-blind trial.
Int J Cosmet Sci.
1991;
13
51-57
- 32
Marquart F X, Bellon G, Gillery P. et al .
Stimulation of collagen synthesis in fibroblast cultures by a triterpene extracted
from Centella asiatica.
Int Rev Connet Tissue Res.
1990;
24
107-120
- 33 Korting H C.
Evidenzbasierte Dermatika und Kosmetika. Plewig G, Kaudewitz P, Sander CA, Hrsg. Fortschritte der praktischen Dermatologie
und Venerologie. Bd. 19. Berlin, Heidelberg; Springer 2004: 548-554
Dr. Stephanie Steckmeier
Klinik und Poliklinik für Dermatologie und Allergologie
Klinikum der LMU
Frauenlobstraße 9–11
80337 München
eMail: stephanie.steckmeier@med.uni-muenchen.de
