New Carvotanacetone Derivatives from Sphaeranthus africanus

Abstract

The dichloromethane extract of the air-dried leaves of Sphaeranthus africanus afforded four new carvotanacetone derivatives (1, 2, 3a, and 3b). Their structures were elucidated by extensive 1D and 2D NMR spectroscopy. Compounds 1–3 exhibited antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa and antifungal activity against Candida albicans, Trichophyton mentagrophytes and Aspergillus niger.

Key words

Sphaeranthus africanus - Asteraceae - carvotanacetone derivatives - antimicrobial

References

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