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DOI: 10.1055/s-0029-1186198
© Georg Thieme Verlag KG Stuttgart · New York
Complete Clinical Response to Neoadjuvant Chemotherapy in a 54-year-old Male with Askin Tumor
Publikationsverlauf
received February 16, 2009
Publikationsdatum:
02. August 2010 (online)
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Abstract
Askin tumor is a tumor of the thoracopulmonary region that most commonly affects children and adolescents. These rare tumors are a form of primitive neuroectodermal tumor and typically carry a poor prognosis. Treatment is multimodal and consists of a combination of neoadjuvant chemotherapy, radical resection, and adjuvant chemo- and radiotherapy or all of the above. Surgery is advocated in most cases. We report a case of Askin tumor in a 54-year-old male who showed rapid and complete response to neoadjuvant chemotherapy. This allowed potentially radical surgery to be avoided. At one-year follow-up he remains disease-free.
Key words
Neoadjuvant therapy - chest wall - sarcoma
References
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- 4 Grier H E, Krailo M D, Tarbell N J et al. Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone. N Engl J Med. 2003; 348 (8) 694-701
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Dr. Jurgen Mulsow
Department of Surgery
Adelaide and Meath Hospital
Tallaght
24 Dublin
Ireland
Telefon: + 35 3 14 14 22 13
Fax: + 35 3 14 14 22 12
eMail: jmulsow@rcsi.ie