Abstract
Insulinomas are rare, mostly benign neuroendocrine tumours with an incidence of approximately four cases per million person per year. Only isolated case reports of insulinomas occurring in pregnancy have been documented. Clinical signs and symptoms of insulinoma appear to be attenuated and, in some cases, even masked by pregnancy. Therefore, in the present overview of insulinomas occurring during pregnancy, special attention is paid to potential factors contributing to the altered insulin response during pregnancy.
Key words
neuroendocrine tumour - hypoglycaemia - insulin resistance - insulin-antagonistic action - gestation
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Correspondence
Dr. K. MüssigMD
Medizinische Klinik IV
Universitätsklinikum Tübingen
Otfried-Müller-Str. 10
72076 Tübingen
Germany
Phone: +49/0/7071/29 836 70
Fax: +49/0/7071/29 27 84
Email: Karsten.Muessig@med.uni-tuebingen.de