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Exp Clin Endocrinol Diabetes 1983; 81(1): 88-90
DOI: 10.1055/s-0029-1210211
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Prevention of Demasculinization and Feminization of the Brain in Prenatally Stressed Male Rats by Perinatal Androgen Treatment1)

G. Dörner, F. Götz, W.-D. Döcke
  • Institute of Experimental Endocrinology (Director: Prof. Dr. G. Dörner), Humboldt-University, Berlin/GDR
1) Professor. Dr. Dr. h. c. G. Sterba on the Occasion of his 60th Birthday.
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Publication History

1982

Publication Date:
17 July 2009 (online)

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Summary

Female rats were exposed to immobilization and illumination stress from day 15—22 of pregnancy. Their male offspring showed demasculinization, i.e. significantly decreased male sexual behaviour, and feminization, i.e. significantly increased female sexual behaviour, in adulthood. This permanent demasculinization and feminization of the brain, induced by prenatal stress, could be prevented by perinatal androgen treatment.