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Exp Clin Endocrinol Diabetes 1983; 82(4): 97-100
DOI: 10.1055/s-0029-1210261
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Effect of Nifedipine on the Adrenocortical and Somatotrophic Secretory Reserve and TSH and Thyroid Hormone Plasma Levels

I. Žofková, M. Neradilová, I. Kimlová, L. Stárka, R. Reisenauer
  • Research Institute of Endocrinology, (Director: MUDr. J. Pečeny, CSc), Prague and Chair of Nuclear Medicine (Director: Prof. MUDr. J. Prokopec, CSc), Faculty of Medicine and Hygiene, Charles University Prague/Czechoslovakia
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Publication History

1982

Publication Date:
17 July 2009 (online)

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Summary

The authors investigated the effect of one week's administration of therapeutic doses of the calcium antagonist nifedipine on the hormone homeostasis of clinically healthy subjects. The insignificant tendency towards an increase of the adrenocorticotrophic and somatotrophic secretory reserve and the unaltered levels of thyrotrophin, triiodothyronine and thyroxine rule out possible-adverse side-effects of the administered therapeutic doses of nifedipine on the hormone balance of the mentioned systems. The authors discuss also the physiological impact of the assessed findings.