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Exp Clin Endocrinol Diabetes 1984; 83(3): 370-372
DOI: 10.1055/s-0029-1210358
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Alpha-Adrenergic Effects on Insulin Release from Isolated Pancreatic Rat Islets Are Influenced by Alpha-Glucosidase

Cz. Wójcikowski1 , V. Maier2 , E. F. Pfeiffer2
  • 1Laboratory of Endocrinology, Institute of Obstetrics and Gynecology, Medical Academy, Gdańsk/Poland
  • 2Department of Internal Medicine I, University of Ulm/FRG
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Publikationsverlauf

1982

1983

Publikationsdatum:
17. Juli 2009 (online)

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Summary

The modification of isolated pancreatic rat islets by pretreatment with alpha-glucosidase abolished the stimulatory action of phentolamine but not changed glucose induced insulin release. In modified islets the inhibitory effect of epinephrine was only slightly changed. The data indicated that alpha-adrenergic receptors may be selectively damaged by alpha-glucosidase.

Key words

Insulin release - isolated islets - alpha-glucosidase