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Exp Clin Endocrinol Diabetes 1984; 84(5): 235-238
DOI: 10.1055/s-0029-1210393
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Natriuretic Properties of [2-p-Ethylphenylalanine] deamino-6-carba-oxytocin (Nacartocin) in Cats

J. Škopková, T. Barth, P. Hrbas, K. Jošt, M. Lebl
  • Department of Biochemistry, Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences (Director: Dr. Ing. K. Šebesta, Dr. Sc.), Prague/Czechoslovakia
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Publication History

1984

Publication Date:
17 July 2009 (online)

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Summary

Nacartocin, a synthetic analogue of oxytocin, [2-L-p-phenylalanine]deamino-6-carba-oxytocin has a specific natriuretic effect in cats. The doses of 0.05—10 μg/kg b.w. (0.05—10 nmols/kg) of Nacartocin applied i.v. caused a several fold increase in the excretion of sodium, while the excretion of kalium was only slightly enhanced.

Key words

Cat - natriuresis - Nacartocin