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Exp Clin Endocrinol Diabetes 1985; 85(2): 228-234
DOI: 10.1055/s-0029-1210441
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Simple Diagnosis of Diabetes Insipidus and Antidiuretic Hormone Excess

L. Kovács, V. Némethova, Y. Gucalová, V. Lehotská, J. Čintala, N. Michajlovskij2 , J. Michaličková, B. Lichardus2
  • 22ndClinic of Pediatrics, Comenius University (Head: Prof. MUDr. J. Michaličkova, DrSc. corresponding member of the Slovak Academy of Sciences) and Institute of Experimental Endocrinology, Centre of Physiological Sciences, Slovak Academy of Sciences (Head: Corresponding member of the Czechoslovak Academy of Sciences L. Macho), Bratislava/Czechoslovakia
Further Information

Publication History

1984

Publication Date:
16 July 2009 (online)

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Summary

The value of information that may be obtained by measuring osmolality of body fluids is not generally appreciated by clinicians. Osmolality determination by freezing point depression is technically simple to perform and requires only 0.2 ml fluid. The simultaneous measurement of plasma and urine osmolality may yield useful information concerning alterations in water homeostasis (diabetes insipidus and antidiuretic hormone excess) and avoid uncomfortable and sometimes hazardous investigations of patients.

Key words

Diabetes insipidus - antidiuretic hormone excess - diagnosis - urine and plasma osmolality