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Exp Clin Endocrinol Diabetes 1985; 85(3): 326-330
DOI: 10.1055/s-0029-1210458
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Prolactin and Thyrotropin Response Thyrotropin Releasing-Hormone in Adolescent Females with Insulin-Treated diabetes Mellitus

J. M. Komorowski1 , Alina Komorowska2 , Hanna Dziatkowiak3 , Irena Owczarczyk1 , Malgorzata Zawodniak3
  • 1Institute of Endocrinology, Łódż Medical Academy (Director: Prof. M. Pawlikowski, M. D.), Łódż/Poland
  • 2Emeritus Professor of Obstetrics and Gynaecology, Łódż Medical Academy, Łódż/Poland
  • 3Institute of Pediatrics, The 2nd Clinic of Pediatrics, Łódż Medical Academy (Head: Prof. S. Nowak, M. D.) Łódż/Poland
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Publikationsverlauf

1984

Publikationsdatum:
16. Juli 2009 (online)

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Summary

Prolactin and thyrotropin response to TRH and basal gonadotropins levels in blood were investigated in insulin-treated adolescent females with regular menstruation cycles (Group I) and menstruation disturbances (Group II) compared with control, healthy girls. No significant differences were found in TSH secretion after TRH administration and basal LH, FSH levels between the observed groups. Blood basal PRL levels were significantly lower in young females in Group II, and a highly increased mobilization of PRL secretion (delta % PRL) — masked hyperprolactinaemia — in all of the groups of diabetic girls was revealed. Cytological examination of vaginal smears confirmed hypoestrogenic status of girls from Group II compared with Group I and the control group.

Key words

Diabetes mellitus - Menstruation disorders - TRH-test