Download PDF
Exp Clin Endocrinol Diabetes 1986; 87(1): 104-107
DOI: 10.1055/s-0029-1210528
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Hormonal Factors Influencing Fractional Excretion of Filtered Sodium in Normal Children

M. Uchiyama, T. Otsuka, Y. Shibuya, K. Sakai
  • Department of Paediatrics (Head: Prof. Dr. K. Sakai), Niigata University School of Medicine, Niigata/Japan
Further Information

Publication History

1985

Publication Date:
16 July 2009 (online)

Also available at
  PDF Download  Permissions and Reprints

Summary

Fractional excretion of filtered sodium (FENa), plasma renin activity (PRA), urinary kallikrein excretion and main urinary metabolite of prostaglandin F2α (PGF MUM) excretion were measured to evaluate the relationship between FENa and these hormonal factors in 33 healthy children aged 8 to 15 years. FENa showed a significant negative correlation with PRA and PGF MUM excretion (P < 0.001, P < 0.01, respectively), suggesting that PRA and PGF MUM are useful investigations in evaluating FENa. Especially PRA is often measured routinely and should be measured first, which may provide useful pathophysiological information on the genesis of abnormal FENa

Key words

FENa - Plasma renin - Kallikrein - Prostaglandin - Children