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Exp Clin Endocrinol Diabetes 1986; 87(1): 108-111
DOI: 10.1055/s-0029-1210529
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Differences in the Content of Glucagon-Like Immunoreactivity in Rat Submaxillary Glands

Elżbieta Paulo1 , H. Keilacker2 , K.-D. Kohnert2
  • 1Department of Animal Physiology (Head: Prof. Dr. sc. nat. J. Surowiak), Institute of Zoology, Jagiellonian University, Krakov/Poland
  • 2Central Laboratory (Head: Dr. sc. nat. M. Ziegler), Central Institute of Diabetes Karlsburg (Director: OMR Prof. Dr. sc. med. H. Bibergeil)/GDR
Further Information

Publication History

1984

Publication Date:
16 July 2009 (online)

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Summary

Two different antisera which specifically reacted with either the C- or N-terminal region of pancreas glucagon were employed to determine the concentration of glucagon and glucagon-like immunoreactivity in extracts from submaxiilary glands of rats.

The content of glucagon and glucagon-like immunoreactivity increased with age and was found to be higher in adult males than in females. Pancreas glucagon immunoreactivity constituted only a small proportion of the total glucagon-like immunoreactivity.

The role that glucagon-like peptides present in the submaxillary gland of rats might play in the glucose homeostasis remains still unknown.

Key words

Glucagon immunoreactivity - Glucagon degradation - Submaxillary gland - Age and sex dependency