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Exp Clin Endocrinol Diabetes 1986; 87(1): 112-115
DOI: 10.1055/s-0029-1210530
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Decreased 133Xe Clearance in the Proximal Femur in Acromegaly

J. Kapitola, J. Marek, I. Jahoda, D. Vilimovská
  • Laboratory for Endocrinology and Metabolism and 3rd Medical Clinic (Head: Prof. MUDr. V. Pacovský, DrSc., corresponding member of Czechoslovak Academy of Sciences), Charles University, Prague/Czechoslovakia
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Publication History

1985

Publication Date:
16 July 2009 (online)

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Summary

Using the 133Xe tissue clearance method, the blood flow in the greater trochanter of the femur was studied in 30 patients with acromegaly. Both the washout rate constant (k2) and blood flow (P2) values are significantly decreased in acromegaly (p < 0.01). There is a significant negative correlation (r = — 0.42, p < 0.05) between the flow values and mean daily concentrations of growth hormone in serum of acromegalic patients. The observation is presented as a preliminary evidence of a possible influence of growth hormone on the blood flow in bone.

Key words

Bone blood flow - 133Xe clearance - Acromegaly