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Exp Clin Endocrinol Diabetes 1986; 87(2): 211-214
DOI: 10.1055/s-0029-1210546
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Androgens, Bone Mineral Content and Hyperostosis Frontalis Interna in Pre-Menopausal Women

Eva Kollin, T. Fehér
  • First Department of Medicine, Semmelweis University Medical School, (Head: Prof. Dr. I. Holló), Budapest/Hungary
Further Information

Publication History

1985

Publication Date:
16 July 2009 (online)

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Summary

Greater than normal bone mineral content, bone width of the radius measured by photon absorptiometry and bone mineral content to bone width ratio found in women with hyperostosis frontalis interna pointed on a generalized alteration of the skeletal system. An increase in serum dehydroepiandosterone, its sulphate and testosterone levels and a significant correlation between serum free dehydroepiandosterone and bone mineral content in subjects without any sign of hirsutism or obesity suggested an involvement of androgens in pathogenesis of this metabolic bone disorder.

Key words

Hyperostosis Frontalis Interna - Metabolic Bone Disease - Androgen Excess - Dehydroepiandrosterone