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Exp Clin Endocrinol Diabetes 1986; 88(5): 200-206
DOI: 10.1055/s-0029-1210597
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Cholecystokinin Affects Water Intake as well as Neurohypophysial Storage of Vasopressin and Oxytocin in the Rat1)2)

J. W. Guzek, Joanna Morawska
  • Department of Pathophysiology (Head: Prof. Dr. med. J. W. Guzek), University School of Medicine, Łódź/Poland
1) This work was supported by a grant No 10.4.04.9 from the Polish Academy of Sciences. CCK (Kabi, Studsvik) was generous gift from Professor St. Konturek, Cracow. 2) Presented at the 50th Congress of the Hungarian Physiological Society (Budapest, July 1—7, 1985).
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Publication History

1986

Publication Date:
16 July 2009 (online)

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Summary

Intracerebroventricular injections of CCK were followed by a decrease of vasopressin and oxytocin content in the neurohypophysis. Water intake and body weight were diminished; serum osmolality and haematocrit index increased. These results suggest a possible regulatory role of CCK in water metabolism and release of neurohypophysial hormones.

Key words

Cholecystokinin - Water intake - Vasopressin - Oxytocin