PDF herunterladen
Exp Clin Endocrinol Diabetes 1987; 89(2): 197-200
DOI: 10.1055/s-0029-1210637
Original

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Dual Effect of Exogenous Progesterone on the Activity of Tyrosine Aminotransferase in the Liver of Female Rats

Š. Németh, E. Viskupič, Daniela Ježová
  • Institute of Experimental Endocrinology (Director: Dr. L. Macho, corresponding member of the Czechoslovak Academy of Sciences), Centre of Physiological Sciences (Director: Dr. J. Zachar, member of the Czechoslovak Academy of Sciences), Slovak Academy of Sciences, Bratislava/Czechoslovakia
Weitere Informationen

Publikationsverlauf

1986

Publikationsdatum:
16. Juli 2009 (online)

Auch verfügbar auf
  als PDF herunterladen  Lizenzen und Reprints

Summary

An as yet undescribed biphasic response of liver tyrosine aminotransferase (TAT) activity to n single administration of a microcrystallic watery suspension of 25 mg of progesterone (Agolutin Depot, SPOFA Praha) is described in adult female rats subjected to immobilization stress for 150 mm. Exaggeration of the stress induced increase of TAT activity 3 and 8 h after hormone administration and its suppression 20 h after it was observed. The stress induced serum corticostorone increase is not correlated with the described changes, however, in non-stressed animals an increased TAT activity at 3 and 8 h after progesterone injection tightly follows the increased plasma corticosterone values. No statistically significant changes were found with respect to liver tryptophan pyrrolase activity.

Key words

Liver tyrosine aminotransferase - Progesterone administration - Serum corticosterone - Immobilization stress