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Exp Clin Endocrinol Diabetes 1988; 91(3): 362-364
DOI: 10.1055/s-0029-1210770
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Does High Cortisol in Uremic Patients Influence Their Glucagon Levels?

M. A. Ivić1 , V. Stefanović
  • Institute of Nephrology and Hemodialysis, Faculty of Medicine, Niš/Yugoslavia
  • 1Institute of Physiology, Faculty of Medicine, Niš/Yugoslavia
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Publication History

1987

Publication Date:
16 July 2009 (online)

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Summary

In view of the data reported by Barseghian and Levine (1980) that cortisol exerts a direct stimulatory influence on glucagon secretion, the relationship between plasma cortisol and glucagon levels in a group of 43 patients with chronic renal failure (CRF) was investigated. A positive correlation (r = 0.363 and 0.811) was found with all patients studied or with 10 patients with urine output above 1000 ml/24 h, respectively. The result obtained suggest that the elevated cortisol levels play some role in the stimulation of glucagon secretion in CRF patients.

Key words

Glucagon - Cortisol - Chronic renal failure patients