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Exp Clin Endocrinol Diabetes 1994; 102(1): 50-53
DOI: 10.1055/s-0029-1211265
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Complete remission of metatasized adrenocortical carcinoma under o,p'-DDD

E. Kornely, R. Schlaghecke
  • Medizinische Klinik und Poliklinik, Abteilung für Endokrinologie und Rheumatologie, Heinrich Heine Universität, Düsseldorf, Germany
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Publication History

Publication Date:
15 July 2009 (online)

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Summary

The case of a 53 year old female patient with metastasized androgen producing adrenocortical carcinoma is presented. After initial adrenalectomy a local relapse had been treated by surgery and external irradiation. Solitary liver metastases had been resected repeatedly Subsequently multiple liver metastases required systemic chemotherapy Treatment with o,p′-DDD (initially 12 g/d, long term treatment 1.5–3 g/d) has resulted in a complete remission for nearly 4 years. Gastrointestinal side effects occurred initially but subsided with dose reduction of o,p′-DDD.

Key words

Adrenocortical carcinoma - o,p′-DDD - systemic chemotherapy - complete remission