Spontaneous complete regression of a rectal cancer

Introduction

Colon carcinogenesis is a multistep process involving initiation, growth, and finally malignant transformation. Most colorectal cancers (CRC) arise through malignant transformation of benign adenomas in a process known as the adenoma-to-carcinoma sequence. Development and growth of CRC have been analyzed retrospectively from sporadic cases including radiographic or endoscopic images of lesions overlooked at initial examinations [1] [2] [3]. Here we describe a unique case of a sessile polyp which showed marked morphological change into a depressed lesion, and, unexpectedly, spontaneous complete regression of biopsy-proven rectal cancer was observed in an extremely short period of 3 months.

References

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