Synthesis of Symmetrical Ketones from Grignard Reagents and 1,1′-Carbonyldiimidazole

Abstract

Coupling reactions of 1,1′-carbonyldiimidazole with Grignard reagents provide a rapid and straightforward method for the synthesis of symmetrical ketones.

Key words

Grignard reactions - coupling - acylations - 1,1′-carbonyldiimidazole - ketones

References

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Aldrich Catalogue, 2009-2010.

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TCI Europe Catalogue, 2008-2009.