Transition-Metal-Free Oxidative Homocoupling of Aryl, Alkenyl, and Alkynyl Grignard Reagents with TEMPO

Abstract

Oxidative homocoupling of aryl, alkenyl, and alkynyl Grignard reagents by using commercially available TEMPO as an organic oxidant is described. These coupling reactions occur highly efficiently without the presence of any transition metal.

Key words

Grignard reagents - oxidative homocoupling - alkoxyamine - nitroxide - persistent radicals

References

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