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Synthesis 2010(14): 2407-2412
DOI: 10.1055/s-0029-1218775
DOI: 10.1055/s-0029-1218775
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
A Stereoselective Aldol Approach for the Total Synthesis of Herbarumin I and Stagonolide A
Further Information
Received
8 March 2010
Publication Date:
05 May 2010 (online)
Publication History
Publication Date:
05 May 2010 (online)
Abstract
A stereoselective total synthesis of phytotoxic compounds herbarumin I and stagonolide A has been achieved utilizing Crimmin’s protocol for non-Evans anti-aldol approach and a ring-closing olefin metathesis reaction as the key steps.
Key words
macrolide - phytotoxic - Evans aldol - olefin metathesis
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