Zusammenfassung
Anliegen Überblick über nichtmedikamentöse Interventionsprogramme mit Wellness-Orientierung
zur Reduktion metabolischer Nebenwirkungen unter einer Neuroleptikatherapie. Methode Literaturrecherche. Ergebnisse Kurzzeitige Gewichtsabnahme ist möglich, Langzeitdaten fehlen. Studien zu Lebensstil-Interventionen
und Wellness-Maßnahmen (Steigerung des Wohlbefindens durch aktive Patientenmitarbeit)
sind kaum vorhanden; bisherige Resultate sind jedoch positiv. Schlussfolgerungen Über ein Gewichtsmanagement hinausgehende Konzepte sind erforderlich. Studien mit
einheitlichen Instrumenten und vergleichbaren Outcome-Maßen zum Aufbau eines validen
Pools von Langzeitdaten sind nötig.
Abstract
Objective Weight gain and metabolic disturbances are growing side effects of a modern antipsychotic
therapy. Different programs were developed to reduce them. This article gives an overview
of existing and evaluated programs. Methods A literature research was made through PubMed. Relevant reviews and intervention
studies were identified. Results Studies with the main outcome variable of weight reductions are numerous, even randomised
controlled trials. Short-term weight loss under antipsychotic treatment is possible,
but there is still a lack of long-term studies. Life style interventions, which include
e. g. physical exercise, are not that common. Also, interventions such as wellness-activities,
which contribute by means of adequate motivation strategies to an enhancement of the
general well-being, are still missing. Present results turned out to be positive.
Conclusions Further programs which exceed weight management are required. There is necessity
for more studies with consistent outcome variables and methods, especially long-term
programs.
Schlüsselwörter
Schizophrenie - Wellness-Maßnahmen - Antipsychotische Medikation - Psychoedukation
- Gewichtszunahme - metabolisches Syndrom
Keywords
schizophrenia - wellness-activities - antipsychotic medication - psychoeducation -
weight gain
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Dr. Monika Brönner
Klinik und Poliklinik für Psychiatrie und Psychotherapie des Klinikums rechts der
Isar der Technischen Universität München
Ismaninger Straße 22
81675 München
eMail: m.broenner@mnet-online.de