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DOI: 10.1055/s-0029-1220648
Sculptra: A Stimulatory Filler
Publikationsverlauf
Publikationsdatum:
04. Mai 2009 (online)
ABSTRACT
Sculptra is a biocompatible, resorbable injectable filler composed of poly-L-lactic acid (PLLA). It falls in the class of a stimulatory filler that creates its effect through encouraging neocollagenesis when injected. As it differs from traditional, static fillers such as hyaluronic acid and collagen, it requires a special understanding of how it works, where it can be used, and how it should be injected. The goal of this article is to review the nature of stimulatory volume replacement with a focus on PLLA and its unique considerations. Both the natural method of volume restoration and the persistence of results of up to 2 to 3 years make this product one worthy of inclusion in the first line of tools for cosmetic rejuvenation as well as for reconstructive soft tissue deficits and lipoatrophy.
KEYWORDS
Sculptra - PLLA - poly-L-lactic acid - filler - lipoatrophy
REFERENCES
- 1 Kates L C, Fitzgerald R. Poly-L-lactic acid injection for HIV-associated facial lipoatrophy: treatment principals, case studies and literature review. Aesthet Surg J. 2008; 28 397-403
- 2 Lowe N J. Optimizing poly-L-lactic acid use. J Cosmet Laser Ther. 2008; 10 43-46
- 3 Mest D R, Humble G M. Duration of correction for human immunodeficiency virus-associated lipoatrophy after retreatment with injectable poly-L-lactic acid. Aesthetic Plast Surg. 2008; , August 14 (Epub ahead of print)
- 4 Dermik Laboratories, Paris, France. Sculptra (injectable poly-L-lactic acid): a patient's guide to treatment with Sculptra. Dermik Laboratories 2006
- 5 Salles A G, Lotierzo P H, Gimenez R, Camargo C P, Ferreira M C. Evaluation of the poly-L-lactic acid implant for treatment of the nasolabial fold: 3-year follow-up evaluation. Aesthetic Plast Surg. 2008; 32 753-756
- 6 Burgess C M. Treatment of facial asymmetry with poly-L-lactic acid: a case study. Aesthetic Plast Surg. 2008; 32 552-554
- 7 Levy R M, Redbord K P, Hanke C W. Treatment of HIV lipoatrophy and lipoathrohy of aging with poly-L-lactic acid: a prospective 3-year follow up study. J Am Acad Dermatol. 2008; 59 923-933
- 8 Engelhard P, Humble G, Mest D. Safety of Sculptra: a review of clinical trial data. J Cosmet Laser Ther. 2005; 7 201-205
- 9 Rendon M. Injectable poly-L-lactic acid versus collagen: efficacy and safety in the correction of nasolabial fold wrinkles. Poster presented at: Sculptra Cosmetic Trial Group 31st Skin Disease Education Foundation March 3–9, 2008 Maui, HI;
- 10 Beer K. A single-center open label study on the use of poly-L-lactic acid for the treatment of moderate to severe scarring from acne or varicella. Dermatol Surg. 2007; 33(Suppl 2) S159-S167
- 11 Schulman M R, Lipper J, Skolnik R A. Correction of chest wall deformity after implant based breast reconstruction using poly-L-lactic acid. (Sculptra). Breast J. 2008; 14 92-96
- 12 Grimaldi M, Gentile P, Labardi L, Silvi E, Trimarco A, Cervelli V. Lipostructure technique in Romberg syndrome. J Craniofac Surg. 2008; 19 1089-1091
- 13 Mest D R, Humble G. Efficacy and impact of retreatment with poly-L-lactic acid (PLLA) in persons with human immunodeficiency virus (HIV)-associated facial lipoatrphy. Poster presented at: American Academy of Dermatology 66th Annual Meeting February 1–5 2008 San Antonio, TX;
Victor LacombeM.D.
Facial Plastic and Reconstructive Surgery, 1128 Sonoma Avenue
Santa Rosa, CA 95405
eMail: drlacombe@hotmail.com