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Am J Perinatol 2009; 26(8): 601-604
DOI: 10.1055/s-0029-1220783
© Thieme Medical Publishers

Neonatal Hepatic Mesenchymal Hamartoma Causing Cardiac Failure and Disseminated Intravascular Coagulopathy

Phyllis Wan1 , Jonathan Susman2 , Jessica Kandel3 , Dominique Jan3 , Elizabeth Heidi Jerome4 , Elvira Parravicini1
  • 1Department of Neonatology, Morgan Stanley Children's Hospital of New York
  • 2Department of Radiology, Columbia Presbyterian Hospital, New York, New York
  • 3Department of Surgery, Columbia Presbyterian Hospital, New York, New York
  • 4Department of Anesthesiology, Columbia Presbyterian Hospital, New York, New York
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Publikationsdatum:
15. April 2009 (online)

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ABSTRACT

Even with advance prenatal diagnostic tools, differentiating among specific types of hepatic masses continues to challenge many physicians. Here, we report a neonate with life-threatening hepatic mass, cardiac failure, and disseminated intravascular coagulopathy, which clinically resembled hepatic hemangioma. A hepatic mesenchymal hamartoma was detected by postmortem pathology.

KEYWORDS

Neonatal hepatic mass - mesenchymal hamartoma - DIC - cardiac failure - embolization

REFERENCES

  • 1 Christison-Lagay E R, Burrows P E, Alomari A et al.. Hepatic hemangiomas: subtype classification and development of a clinical practice algorithm and registry.  J Pediatr Surg. 2007;  42 62-67
    CrossrefPubMedGoogle Scholar
  • 2 Isaacs H. Fetal and neonatal hepatic tumors.  J Pediatr Surg. 2007;  42 1797-1803
    CrossrefPubMedGoogle Scholar
  • 3 Stringer M D, Alizai N K. Mesenchymal hamartoma of the liver: a systemic review.  J Pediatr Surg. 2005;  40 1681-1690
    CrossrefPubMedGoogle Scholar
  • 4 Von Schweinitz D. Neonatal liver tumors.  Semin Neonatol. 2003;  8 403-410
    CrossrefPubMedGoogle Scholar
  • 5 Akiyoshi K, Mizote H, Tanaka Y, Nakagawa M. Capillary hemangioma of the liver with Kassabach-Merritt syndrome in a neonate: report of a case.  Surg Today. 2000;  30 86-88
    CrossrefPubMedGoogle Scholar
  • 6 Mulrooney D A, Carpenter B, Georgieff M et al.. Hepatic mesenchymal hamartoma in a neonate: a case report and review of literature.  J Pediatr Hematol Oncol. 2001;  23 316-317
    CrossrefPubMedGoogle Scholar
  • 7 Ontachi Y, Asakura H, Omote M, Yoshida T, Matsui O, Nakao S. Kasabach-Merritt syndrome associated with giant liver hemangioma: the effect of combined therapy with danaparoid sodium and tranexamic acid.  Haematologica. 2005;  90(suppl) ECR29
    PubMedGoogle Scholar
  • 8 Rao S P, Bhagavath S, Chen C K, Tolete-Velcek F. Mesechymal hamartoma of the liver in an older child: association with disseminated intravascular coagulation.  Med Pediatr Oncol. 1984;  12 112-115
    CrossrefPubMedGoogle Scholar
  • 9 Chou S Y, Chiang H K, Chow P K, Wu C F, Liang S J, Hsu C S. Fetal hepatic hemangioma diagnosed prenatally with ultrasonography.  Acta Obstet Gynecol Scand. 2005;  84 301-302
    CrossrefPubMedGoogle Scholar
  • 10 Laberge J M, Patenaude Y, Desilets V et al.. Large hepatic mesenchymal hamartoma leading to mid-trimester fetal demise.  Fetal Diagn Ther. 2005;  20 141-145
    CrossrefPubMedGoogle Scholar
  • 11 Dickinson J E, Knowles S, Phillips J M. Prenatal diagnosis of hepatic mesenchymal hamartoma.  Prenat Diagn. 1999;  19 81-84
    CrossrefPubMedGoogle Scholar
  • 12 Carta M, Maresi E, Giuffrè M et al.. Congenital hepatic mesenchymal hamartoma associated with mesenchymal stem villous hyperplasia of the placenta: case report.  J Pediatr Surg. 2005;  40 E37-E39
    PubMedGoogle Scholar
  • 13 Yen J B, Kong M S, Lin J N. Hepatic mesenchymal hamartoma.  J Paediatr Child Health. 2003;  39 632-634
    PubMedGoogle Scholar
  • 14 Siddiqui M A, McKenna B J. Hepatic mesenchymal hamartoma: a short review.  Arch Pathol Lab Med. 2006;  130 1567-1569
    PubMedGoogle Scholar

Phyllis WanM.D. 

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