Aktuelle Rheumatologie 2009; 34(3): 157-163
DOI: 10.1055/s-0029-1225368
Übersichtsarbeit

© Georg Thieme Verlag KG Stuttgart · New York

Krankheitsaktivitätsmessung im klinischen Alltag bei Spondyloarthritiden

Disease Activity Measures for Spondyloarthritides in Clinical PracticeJ. Hermann 1 , D. Zauner 1 , W. Graninger 1
  • 1Divison of Rheumatology, Department of Internal Medicine, Graz, Austria
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Publikationsverlauf

Publikationsdatum:
07. Juli 2009 (online)

Zusammenfassung

Spondyloarthritiden stellen eine Gruppe von entzündlichen Wirbelsäulen- und Gelenkserkrankungen mit zahlreichen extraartikulären Manifestationen dar. Die Beurteilung der Krankheitsaktivität ist deshalb aufwendig und zeitintensiv, wobei nur für die ankylosierende Spondylitis und die Psoriasisarthritis ausreichend validierte Parameter zur Verfügung stehen. Für die Beurteilung der Krankheitsaktivität der AS im klinischen Alltag können neben dem zusammengesetzten Bath Ankylosing Spondylitis Disease Activity Index auch die Einzelparameter nächtlicher Rückenschmerz, Intensität und Dauer der Morgensteifigkeit und Patienten-orientierte Beurteilung der globalen Krankheitsaktivität empfohlen werden. Zur Beurteilung der Krankheitsaktivität der Psoriasisarthritis sollten im klinischen Alltag die Aktivität der peripheren Arthritis, die Aktivität der Hauteffloreszenzen und die Patienten-orientierte globale Beurteilung der Krankheitsaktivität herangezogen werden.

Abstract

Spondyloarthritides are a group of inflammatory rheumatic diseases that affect the axial and peripheral skeleton and also extraskeletal organs. To comprehensively estimate the activity of the diseases, a whole range of parameters covering all aspects of the disease would therefore be necessary but valid parameters have been developed only for patients with ankylosing spondylitis and psoriatic arthritis. It has been shown that the Bath ankylosing spondylitis activity score as a composite measure and single items such as nocturnal pain, intensity and duration of morning stiffness, patients global assessment of disease activity and the Maastricht ankylosing spondylitis enthesitis index are valid parameters to estimate AS disease activity in clinical practice. To estimate the disease activity of psoriatic arthritis in clinical practice, recommended parameters include the activity of peripheral arthritis and psoriasis, patients’ global assessment of disease activity, and physical function.

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Korrespondenzadresse

Dr. Josef Hermann

Division of Rheumatology

Internal Medicine

Auenbruggerplatz 15

8036 Graz

Austria

Telefon: +43/316/385 77 79

Fax: +43/316/385 78 13

eMail: josef.hermann@medunigraz.at